Who'd Be The Number 1 NFL Pick?

The NFL's overall No. 1 pick received a contract worth almost $50 million and got his first start on Sunday for the San Francisco 49ers against the Indianapolis Colts. Alex Smith said he expected a tough game and he proved that statement to be correct.

He threw 4 interceptions, lost a fumble and was sacked five times in a 28-3 loss to the Colts, the NFL's last unbeaten team. He was 9 of 23 passing for under 75 yards.

"No one said this was going to be easy," he said. "I wasn't happy with all the turnovers I had today," he said. "When you turn the ball over, it makes it tougher for your team to win." True.

SF laid their hands on the ball only eleven times and finished their second game in a row without an offensive touchdown.